| | Accession Number | 5001777 |
| | Title | Contaminant-related activities and synoptic reviews in support of client agencies in the |
| | Department of the Interior |
| | Project Description | The Interagency Testing Committee (ITC) of the Toxic Substances Control Act (TSCA) was |
| | enacted in 1976 as an independent advisory group to the Administrator of the U.S. EPA. The ITC |
| | prioritizes and coordinates the testing of TSCA-regulable chemicals, recommends chemicals for |
| | testing to the Administrator in a Priority Testing List (PTL), publishes semi-annual reports in the |
| | Federal Register, reviews toxicological data submissions from chemical manufacturers, and |
| | develops dossiers on chemicals of concern. By law this action requires that all manufacturers and |
| | importers of these chemicals submit production and exposure data, and results of health and |
| | safety testing for our review. Pending review of these data, additional testing of the chemicals may |
| | be designated by the ITC. The objective of our involvement in this activity is to generate |
| | ecotoxicological data that will be of value to management of natural resources under the |
| | stewardship of the Department of the Interior. The Interagency Coordinating Committee on the |
| | Validation of Alternative Methods , as established by Public Law 106-545 is responsible for the |
| | evaluation of toxicological testing methods which reudce dependency on animal subjects for the |
| | protection of human health and the environment. The objective of our involvement is to contribute |
| | an ecological perspective to this statutory committee. The U.S. EPAs Endocrine Disruptor |
| | Screening and Testing Advisory Committee (EDSTAC) was established to advise the Agency on |
| | development of screening and testing programs for estrogenic substances and other endocrine |
| | disruptors. Such screening and testing is required under provisions of the 1996 Food Quality |
| | Protection Act (FQPA) and 1996 amendments to the Safe Water Drinking Act. The committee |
| | meets monthly to address endocrine disrupting principals, priority setting for generating new data, |
| | methods for screening and testing, and communication and public outreach issues. Collaborative |
| | efforts with Dr. Richard Shore of the Institute of Terrestrial Ecology, Monks Wood, England were |
| | undertaken to coedit a book entitled Ecotoxicology of Wild Mammals. This effort will provide |
| | extremely valuable information and guidance on toxicological thresholds of wild mammals to |
| | natural resource managers and scientists worldwide. |
| | Keywords | ecotoxicology, endocrine disruptors, risk assessment, toxic substances control act, wild |
| | mammals, |
| | Principal | Barnett A Rattner, USGS Patuxent Wildlife Research Center: Barnerr_Rattner@usgs.gov; |
| | Investigators |
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