| Patuxent Science Meeting 2006 Poster Abstract |
| | Effects of chlorfenapyr on birds |
| | Albers PH, Klein PN, Green DE, Melancon MJ, Bradley B, Noguchi G |
| | A 2-year study was conducted to provide information needed for the development of diagnostic |
| | criteria for chlorfenapyr toxicosis. In the first year, male mallard ducks were fed diets containing |
| | concentrations of 0, 2, 5, or 10 ppm technical chlorfenapyr for 10 weeks, or 5 ppm of a |
| | formulated product for 4 weeks. Survival, body weight, feed consumption (removal), behavior, |
| | and molt progression were monitored. Feed and liver were analyzed for chlorfenapyr and two |
| | metabolites. Five of 10 ducks in the 10 ppm group died and neurotoxic effects were observed in |
| | the 5 and 10 ppm groups. Feed removal increased for ducks receiving chlorfenapyr and body |
| | weights of 5 and 10 ppm ducks were reduced. Loss of body fat, muscle atrophy, and bile |
| | retention were suggestive of metabolic disruption or a decreased ability to digest and absorb |
| | nutrients. Liver and kidney weight/body weight ratios exhibited a positive response to |
| | concentrations of chlorfenapyr in the diet. The study design for the second year was changed |
| | to better evaluate observed abnormalities in nerve tissue. |
| | Friday, September 22, 2006 |